A 67-year-old man with an eventually fatal adenocarcinoma of the colon developed an umbilical metastatic lesion. The lesion was excised and biopsy studies showed columnar cells with basophilic nuclei in upper and middle thirds of the dermis forming the glandular arrangement of an adenocarcinoma.
Zeligman I, Schwilm A. Umbilical Metastasis From Carcinoma of the Colon. Arch Dermatol. 1974;110(6):911-912. doi:10.1001/archderm.1974.01630120057013