Histiocytosis Syndrome. Presented by David Feingold, MD, Elizabeth Spivack, MD.
A 33-year-old white woman was admitted to the hospital in 1964 for severe acne vulgaris and neurotic excoriations. She had had a moderate degree of acne vulgaris as a teenager and young adult; the condition was treated by tetracycline therapy, radiotherapy, and corticosteroid injection of the cysts. During her hospitalization she received tetracycline, a drug comprised of norethynodrel and mestranol, (Enovid), and psychotherapy. Later that year she was again admitted and had multiple draining pustules and inflammatory lesions of the face and groin. Culture studies of all lesions showed group A β-hemolytic streptococci and the infections cleared while the patient received appropriate antibiotic therapy.The patient was hospitalized again in 1969 for treatment of widespread, purulent ulcerative lesions thought to be factitial in origin. In 1971, because of recurrent axillary infections, she had an axillary excision for hidradenitis suppurativa.
Hadley TP. NEW ENGLAND DERMATOLOGICAL SOCIETY. Arch Dermatol. 1974;110(6):964. doi:10.1001/archderm.1974.01630120092032