Histological findings of the inflammatory lesions of scabies are distinctive enough to guide the pathologist in the direction of this diagnosis. It is characterized by a combination of an acute, vesicular, eczematous type of epidermal change and an erythema multiforme type of dermal reaction. When this combination is present, a search should be made to expose the organism in tissue sections or in scrapings of the cutaneous lesions.
Hejazi N, Mehregan AH. ScabiesHistological Study of Inflammatory Lesions. Arch Dermatol. 1975;111(1):37-39. doi:10.1001/archderm.1975.01630130039003