To the Editor.—
Porphyria cutanea tarda (PCT), in its symptomatic form, characteristically occurs in the middle-aged adult as a photosensitivity disease with bullae. Later, hyperpigmented scars occur primarily on sun-exposed areas of the body. There is an associated overproduction of uroporphyrins and often coproporphyrins in the urine and feces. Since the original description of PCT by Waldenström in 1937,1 there has been extensive research about the causes of this complex disease. It is well-documented that alcoholism and frank cirrhosis can precede the onset of PCT. More recently, PCT has been associated with estrogen therapy,2 altered iron metabolism,3,4 hexachlorobenzene ingestion,5,6 and lupus erythematosus.7 Recently, we have observed a case of PCT associated with lymphosarcoma and thought that it would be worth reporting.
Report of a Case.—
A 63-year-old woman was admitted to Albany Medical Center Hospital with a 14-month history of successive crops of bullae on
Rayhanzadeh S, Shoss RG, Noyes J. Porphyria Cutanea Tarda Associated With Lymphosarcoma. Arch Dermatol. 1975;111(1):129. doi:10.1001/archderm.1975.01630130131020