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To the Editor.—
In reply to the letter from Dr. Thomas Cochrane of Ayr, Scotland, in which he reported failure to confirm our results of gratifying relief with vitamin E in post-herpes zoster neuralgia, we would suggest a much longer trial than ten weeks. Since our report in the Archives (108:855-856, 1973), we have not had occasion to treat any additional cases of chronic post-herpes zosterlgia, nor have any of the nine patients who were successfully treated returned for further observobservation.We would again emphasize the importance of high dosage (1,200 to 1,600 international units [IU]) of vitamin E in the form of D-alpha tocopheryl acetate or succinate over a period of six months or more, and the importance of avoiding any medication, including mixed vitamins containing inorganic iron, which combines with and inactivates vitamin E. This prohibition also applies to white flour and to many cereals that are reinforced with iron. Conjugated estrogens also exert an antagonistic effect on vitamin E. Diets high in unsaturated fats increase
Ayres S, Richard-Mihan R. Post-Herpes Zoster Neuralgia: Response to Vitamin E Therapy-Reply. Arch Dermatol. 1975;111(3):396. doi:10.1001/archderm.1975.01630150116021