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April 1975

Lymphomatoid Granulomatosis of the SkinA New Clinicopathologic Entity

Author Affiliations

From the Department of Dermatology (Dr. Minars) and the Department of Pathology (Drs. Kay and Escobar) of the Medical College of Virginia, Richmond, Va.

Arch Dermatol. 1975;111(4):493-496. doi:10.1001/archderm.1975.01630160083009

Lymphomatoid granulomatosis is a necrotizing arteritis primarily affecting the lungs but also found in the skin, kidneys, central nervous system, and other extrapulmonary sites. Cutaneous involvement occurred in 45% of the cases described by Liebow in his original series.

Light microscopy studies were performed. The IgA and IgG levels were slightly decreased and the IgE level was elevated. Cell-mediated immunity was impaired. No viruses were isolated or identified by immunofluorescence.

A man had cutaneous lesions as the first sign of lymphomatoid granulomatosis.