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June 1975

Cat-Scratch Disease Skin TestStudies of Specificity and Histopathologic Features

Author Affiliations

From the Department of Medicine, Cleveland Metropolitan General Hospital, Case Western Reserve University School of Medicine, Cleveland. Dr. Czarnetzki is now with the Johns Hopkins University at the Good Samaritan Hospital, Baltimore, and Dr. Belcher is now at Mayo Clinic, Rochester, Minn.

Arch Dermatol. 1975;111(6):736-739. doi:10.1001/archderm.1975.01630180064007

Microscopical examination of biopsy specimens from cat-scratch skin test sites, performed in patients with catscratch disease (CSD), sarcoidosis, tuberculosis, and other granulomatous diseases, showed noncaseating granulomatous dermal inflammation in 11 of 12 patients with CSD and in some patients with sarcoidosis or tuberculosis. Biopsy of cat-scratch skin test sites may be a useful ancillary procedure in diagnosing CSD if other granulomatous diseases are excluded.