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June 1975

The Sign of Leser-Trélat

Author Affiliations


Arch Dermatol. 1975;111(6):792-793. doi:10.1001/archderm.1975.01630180120022

To the Editor.—  The sign of Leser-Trélat, ie, the development of multiple pruritic seborrheic keratoses, either preceding or concurrent with the development of internal carcinomas, is a sign which has not been totally accepted by the dermatologic community.1 Recently we saw a patient with a history of prostatic carcinoma who subsequently developed multiple seborrheic keratoses that were essentially asymptomatic.

Report of a Case.—  A 64-year-old man was seen in August 1974 with a chief complaint of "black moles of the back." He acknowledged the presence of this type of lesion for several years but sought medical attention at this time because of a sudden increase in their number during the preceding months. There was no history of pruritus. Medical history showed adenocarcinoma of the prostate first treated by transurethral resection in the spring of 1973. He was treated chemotherapeutically for recurrence of his genitourinary disorder in August 1974.Physical examination

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