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Article
July 1975

Low-Dosage Cytarabine Therapy for Herpes Zoster With Pneumonia

Author Affiliations

From Western Pennsylvania Hospital and the Division of Dermatology, University of Pittsburgh, Pittsburgh.

Arch Dermatol. 1975;111(7):910-912. doi:10.1001/archderm.1975.01630190100015
Abstract

Disseminated herpes zoster infection is frequently fatal. Cytarabine (cytosine arabinoside), a drug of variable efficacy, has offered some hope in the treatment of this condition. In this case of disseminated herpes zoster infection with pneumonia, there was remarkable recovery after lowdosage cytarabine infusion. The findings suggest that doses of the drug not exceeding 30 mg/sq m of body surface per 24 hours (30 mg/sq m/24 hr) may well be virucidal but not cytohematotoxic.

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