[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
July 1975

Variegate Porphyria

Author Affiliations

McKeesport, Pa

Arch Dermatol. 1975;111(7):926-927. doi:10.1001/archderm.1975.01630190116021

To the Editor.—  The case of a 27-year-old woman with variegate porphyria was presented by Freinkel and Ashman to the Chicago Dermatological Society, March 21, 1973, in the Archives (110:653-654, 1974). The findings are similar to those in a 31-year-old woman whom I have been following up for the past two years. These findings include the following: development of bullae and pigmentation of the dorsa of the hands, particularly after sun exposure; episodes of abdominal distress, the history of which was originally overlooked; quantitative 24-hour urine values in which the values of the coproporphyrins exceeded those of the uroporphyrins; and absence of measurable urinary porphobilinogen. There was no history of intake of drugs or unusual amounts of alcohol. Despite a negative screening test for urinary porphobilinogen, uroporphyrins, and coproporphyrins, a quantitative 24-hour urinary porphyrin study was done because the initial clinical features were so consistent with porphyria cutanea tarda. This

First Page Preview View Large
First page PDF preview
First page PDF preview