To the Editor.—
Various substrates have been used for the indirect immunofluorescence technique.1,2 Human skin, theoretically, should be more sensitive and specific, but limited data, sources, and standardization have made this impractical. We at Cook County Hospital have been using recipient site plugs from hair transplants as a source of immunofluorescence substrate.We realize that human skin has been used before as substrate3 for indirect immunofluorescence, but this material is often unavailable.3Since one patient may have from 150 to 250 plugs, many substrate samples can be obtained and standardized. We hope to report more extensively on our findings in the future.
Barsky S, Storino W, Ainis H, Bennin B, Bloom R. Hair Transplant Plugs Sites as Source of Immunofluorescence Substrate. Arch Dermatol. 1975;111(8):1071. doi:10.1001/archderm.1975.01630200131021