• Two cases of nocardial mycetoma were successfully treated with a mixture of trimethoprin and sulfamethoxazole (Bactrim). The patient in case 1 showed resistance to treatment with antibiotics and sulfamethoxypyridazine, and the causal agent of the disease could not be isolated. In case 2, bone involvement was seen; the causal agent was N asteroides. No adverse effects of the drug occurred in a period of treatment ranging from three to nine months.
(Arch Dermatol 111:1345:1348, 1975)
Nitidandhaprabhas P, Sittapairochana D. Treatment of Nocardial Mycetoma With Trimethoprim and Sulfamethoxazole. Arch Dermatol. 1975;111(10):1345-1348. doi:10.1001/archderm.1975.01630220109013