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October 1975

Malignant Melanomas

Author Affiliations

Köln, West Germany

Arch Dermatol. 1975;111(10):1365. doi:10.1001/archderm.1975.01630220129021

To the Editor.—  In the Archives (110:599-601, 1974), Okun et al reported malignant melanomas developing from intradermal nevus. Dr. Okun sent the histological slides to Professor Illig, chairman of the Department of Dermatology of the University of Gieβen, in West Germany, who sent them to me. Published already in the Archives (92:69-72,1965) is a report of a metastasis of a malignant melanoma found surrounded by a capsule of connective tissue beneath an intradermal nevus, revealing lipomatous degeneration. A transition between the nevus and the metastasis is not found. In contrast, the nevus is separated by the capsule of collagenous fibers mentioned previously. I do not see a malignant melanoma at all. In my opinion, a cellular blue nevus is combined with an intradermal nevus. The peculiar vesicle-like cells that are diagnosed as cells of a malignant melanoma by Okun et al are a variety of nevus cells that I described

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