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November 1975

Mechlorethamine in PsoriasisFurther Attempts to Induce Immunological Tolerance

Author Affiliations

From the Dermatology Service, Veterans Administration Hospital and the Department of Dermatology, University of Miami School of Medicine, Miami, Fla (Drs. Breza, Kechijian, and Taylor). Dr. Breza is now at the US Army Hospital, Fort Campbell, Ky.

Arch Dermatol. 1975;111(11):1438-1439. doi:10.1001/archderm.1975.01630230040005

• Further attempts to induce immunological tolerance in 29 psoriatic patients treated topically with mechlorethamine hydrochloride have not been successful using the intravenous route. The rate of sensitization achieved (65%) is not substantially different from the rate for those patients who had no attempt to induce tolerance (55.5%).

(Arch Dermatol 111:1438-1439, 1975)