• We report 32 patients with erythema nodosum leprosum (ENL). Twenty-two patients developed ENL before beginning chemotherapy. The recognition that ENL in the absence of chemotherapy is not an uncommon event is of importance, not simply as a fact in and of itself, but because this observation raises provocative questions when placed in the context of current ideas concerning ENL. ENL should be regarded as a manifestation of leprosy, not necessarily as a complication of its therapy.
(Arch Dermatol 111:1575-1580, 1975)
Rea TH, Levan NE. Erythema Nodosum Leprosum in a General Hospital. Arch Dermatol. 1975;111(12):1575-1580. doi:10.1001/archderm.1975.01630240031005