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December 1975

Contact Urticaria From Cobalt Chloride

Author Affiliations


From the Dermatology Service, Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco (MAJ Smith and LTC Odom) and the Department of Dermatology, University of California San Francisco Medical Center (Dr Maibach).

Arch Dermatol. 1975;111(12):1610-1611. doi:10.1001/archderm.1975.01630240066013

• Cobalt chloride should be added to the ever growing list of contact urticants. This chemical is frequently used as a color indicator in provocative sweat testing. In this case, contact urticaria was probably nonimmunologic in origin. Since diphenhydramine and 48-80 (polymonine) block this reaction to cobalt chloride, vasoactive amines are at least partially responsible for the urticaria.

(Arch Dermatol 111:1610-1611, 1975)