To the Editor.—
Bushkell et al1 have reported important immunofluorescent findings in a case of herpes gestationis that confirm and extend the observation by Provost and Tomasi2 that there is a deposition of complement components and immunoglobulins along the basement membrane in these patients. We have recently cared for a patient with herpes gestationis in whom immunofluorescence studies established the diagnosis in the prebullous phase of the disease.
Report of a Case.—
A 26-year-old woman developed a pruritic nodule near the umbilicus at 28 weeks gestation of her fourth pregnancy. The nodule enlarged during a period of days to form an annular lesion 6 cm in diameter that encircled the umbilicus. Other nodular and annular lesions consisting of red urticarial rings with caféau-lait-colored centers arose elsewhere on the trunk, and a diffuse red induration appeared on the palms and soles. Studies for fungal and internal disease were negative,
Reid LH, Sams WM. Herpes Gestationis. Arch Dermatol. 1976;112(6):882. doi:10.1001/archderm.1976.01630300078022