• We encountered an unusual case of pemphigus foliaceus in which there were early clinical signs of dermatitis herpetiformis with eosinophilic spongiosis histologically. Numerous authors have appreciated that eosinophilic spongiosis occurs in early pemphigus foliaceus, usually in the preacantholytic stage when the lesions may clinically simulate dermatitis herpetiformis. Recognition of eosinophilic spongiosis may help differentiate early pemphigus from other vesiculobullous disorders.
(Arch Dermatol 112:1148-1152, 1976)
Osteen FB, Wheeler CE, Briggaman RA, Puritz EM. Pemphigus FoliaceusEarly Clinical Appearance as Dermatitis Herpetiformis With Eosinopholic Spongiosis. Arch Dermatol. 1976;112(8):1148-1152. doi:10.1001/archderm.1976.01630320054017