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Article
August 1976

Lichen Sclerosus et Atrophicus Associated With Turner Syndrome

Arch Dermatol. 1976;112(8):1174. doi:10.1001/archderm.1976.01630320072023
Abstract

To the Editor.—  Recently, we saw a patient with Turner syndrome and lesions of lichen sclerosus et atrophicus (LSA) in the anogenital region. A similar association of Turner syndrome with lichen sclerosus et atrophicus could not be found in the literature.

Report of a Case.—  A woman born in 1946 had Turner syndrome. She began estrogen therapy in 1960 because of amenorrhea and lack of secondary sex characteristics. In 1966, examination of buccal smears and study of chromosomes showed a chromatinnegative nucleus and the 45-X0 chromosome. In April 1974, the patient developed itching on the left side of the vulva. This gradually became more severe and extended to the right side of the vulva and to the perianal region. Examination in November 1974 revealed areas of white discoloration with some hardening and atrophy in labia majora, labia minora, around the urethral meatus, and extending perianally. There were few superficial erosions

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