• Three patients with relapsing polychondritis were treated successfully with dapsone. Mounting evidence suggests an immune-related pathogenesis for relapsing polychondritis. Dapsone may be effective in certain immune-related diseases because of its inhibition of lysosomal enzymes.
(Arch Dermatol 112:1286-1288, 1976)
Barranco VP, Minor DB, Solomon H. Treatment of Relapsing Polychondritis With Dapsone. Arch Dermatol. 1976;112(9):1286-1288. doi:10.1001/archderm.1976.01630330048013