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Article
November 1976

Induction of Glycosuria and Hyperglycemia by Topical Corticosteroid Therapy

Author Affiliations

From the Departments of Dermatology and Pathology, Mount Sinai Medical Center, Miami Beach, Fla.

Arch Dermatol. 1976;112(11):1559-1562. doi:10.1001/archderm.1976.01630350035009
Abstract

• A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion. A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%. Two additional patients with mildly abnormal responses to glucose tolerance tests showed no evidence of altered glucose metabolism when treated with halcinonide cream in a similar manner.

(Arch Dermatol 112:1559-1562, 1976)

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