To the Editor.—
The association of Hansen disease and lymphoma has been a recurrent, vexing problem.1-3 We are currently seeing two patients with inactive lepromatous leprosy who were found to have Hodgkin disease within a three-month interval while residing in the Carville leprosarium.
The condition of a 57-year-old man with lepromatous leprosy since 1939, inactive since 1953, was diagnosed in 1974 as Hodgkin disease. Since 1941, the patient has been under continuous treatment with sulfoxone sodium for his Hansen disease.He had intermittent fever, episodic delerium, and costovertebral pain when first seen. Large, nontender lymph nodes were present in the right anterior cervical region and right supraclavicular region. He also had large, tender posterior cervical nodes, as well as hepatosplenomegaly.Laboratory findings were as follows: WBC count, 11,500/cu mm, with normal differential cell count; hematocrit, 42.7%; ESR, 73 mm/1 hr (Westergren); SGOT, 67 IU; total bilirubin, 1.0
Gergatz SJ, Drook JE, Kaiser JS, Crutcher WA. Hodgkin Disease in Hansen Disease. Arch Dermatol. 1977;113(1):112. doi:10.1001/archderm.1977.01640010114030