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March 1977

An Unusual Variant of Darier Disease

Arch Dermatol. 1977;113(3):374. doi:10.1001/archderm.1977.01640030120023

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To the Editor.—  The article by Peck et al (112:495, 1976), reporting the cornifying variant of Darier disease was most interesting. The variant is not unique in the usual meaning of the word, for the authors refer to a second similar case found in the literature.We have been following a patient with a cornifying variant of Darier disease for over ten years.

Report of a Case.—  A 35-year-old man came to the dermatology clinic because of painful, malodorous vegetations on the lower legs. Lesions typical of the disease, both clinically and histologically, were present on his trunk, arms, and legs. His secondary infection cleared with tetracycline and acetic acid compresses. He was then lost to follow-up for 11 years, when he again returned because of painful, malodorous legs. Verrucous cornifying growths were present on the sides of the lower part of his legs (Fig 1 and 2), and the

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