• Betamethasone 0.1% as valerate in an ointment base and fluocinonide 0.05% in a fatty alcohol propylene glycol (FAPG) base have been compared in a double-blind trial of 76 patients with either eczema or psoriasis. The results show betamethasone valerate ointment to be significantly (P < .05) superior to fluocinonide FAPG in the treatment of both these skin conditions. In the light of publications from other studies on betamethasone valerate cream this trial indicates that the ointment base considerably increases the efficacy of betamethasone valerate.
(Arch Dermatol 113:599-601, 1977)
Munro DD, Robinson TWE, du Vivier AWP, France DM, Clayton R, Sparkes CG. Betamethasone Valerate Ointment Compared With Fluocinonide FAPGUse in the Treatment of Psoriasis and Eczema. Arch Dermatol. 1977;113(5):599-601. doi:10.1001/archderm.1977.01640050059006