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June 1977

Trioxsalen Bath and Ultraviolet Light Treatment of Psoriasis

Author Affiliations

Upsala, Sweden

Arch Dermatol. 1977;113(6):852. doi:10.1001/archderm.1977.01640060148032

To the Editor.—  Eighteen light-tolerant patients with widespread psoriasis were treated with 15 minutes of a 37 C warm bath with 50 mg of trioxsalen in 100 liters of water. The trioxsalen added was dissolved in 100 ml of 70% alcohol. Immediately after the bath, the skin was irradiated with a set of lamps for ten to 300 seconds at a distance of 60 cm.1 The lamp gives 0.8M W/sq cm of ultraviolet (UV)-B and 13M W/sq cm of UV-A. The treatment was given five days per week. One arm was left for treatment with coal tar bath, UV light, and stiff dithranol paste.2 After two to five weeks, the psoriasis had almost or completely healed on the trioxsalentreated skin. The arm treated with the Ingram regimen2 healed slower in nine patients, faster in one, and at the same rate in the others. It is possible that

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