• A detailed evaluation of the clinical and histologic manifestations of eosinophilic fasciitis is described in a 22-year-old woman. Scleroderma-like skin involvement is associated with eosinophilia and hypergammaglobulinemia. Visceral and serologic manifestations of a generalized scleroderma are lacking. Results of a biopsy showed severe thickening of the deep fascia accompanied by an infiltration of lymphocytes and plasma cells. This syndrome must be differentiated from generalized scleroderma because eosinophilic fasciitis has a benign course and may benefit from systemic corticosteroid therapy.
(Arch Dermatol 113:1092-1093, 1977)
Krauser RE, Tuthill RJ. Eosinophilic Fasciitis. Arch Dermatol. 1977;113(8):1092-1093. doi:10.1001/archderm.1977.01640080094017