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Article
August 1977

Hereditary Syringomas

Arch Dermatol. 1977;113(8):1133. doi:10.1001/archderm.1977.01640080135039
Abstract

To the Editor.—  There are a large number of epidermal appendage tumors of the skin, and they have been carefully classified according to clinical appearance, light and electron microscopical structure, and enzyme histochemistry.1,2 Most of these tumors appear to be acquired and are representative of developmental defects, although disorders such as the basal cell nevus, trichoepithelioma, cylindroma, and steatocystoma multiplex have a genetic basis, and they are inherited in an autosomal dominant manner.3 Of these disorders, however, in only the basal cell nevus syndrome is a second type of skin lesion—palmar keratoses and pits—observed. This report describes a patient with both syringomas of the face and palmar keratoses, whose mother had similar lesions.

Report of a Case.—  The patient was a 65-year-old woman who requested removal of several lesions of the face that had developed when she was in her teens. She had also noted keratotic lesions of

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