• Mycophenolic acid is an antimetabolite used experimentally for the treatment of psoriasis. Thirty-eight patients were treated with mycophenolic acid. A doubleblind, placebo-controlled study demonstrated the efficacy of mycophenolic acid (P < .01). A long-term safety study showed the occurrence of hematologic abnormalities, viral infections, and carcinoma. The position of mycophenolic acid in the therapeutic treatment of psoriasis must await the results of a multicenter cooperative study.
(Arch Dermatol 113:1203-1208, 1977)
Lynch WS, Roenigk HH. Mycophenolic Acid for Psoriasis. Arch Dermatol. 1977;113(9):1203-1208. doi:10.1001/archderm.1977.01640090051004