• An 83-year-old woman had nodular primary localized cutaneous amyloidosis. Several anetodermic, bullous-appearing lesions were observed. Biopsy showed massive amyloid deposition with destruction of elastic and collagen fibers, but no bullous formation. It was concluded that the amyloid deposition induced anetodermic changes creating the clinical appearance of bullae.
(Arch Dermatol 113:1248-1249, 1977)
Chapel TA, Birmingham DJ, Malinowski YE. Nodular Primary Localized Cutaneous Amyloidosis. Arch Dermatol. 1977;113(9):1248-1249. doi:10.1001/archderm.1977.01640090096016