Allergic reactions after direct contact of formaldehyde with the skin of a previously sensitized individual are usually eczematous. This report describes a patient who developed a contact urticaria after she handled leather that qualitatively was found to contain minimal amounts of formaldehyde.
Report of a Case
A 28-year-old woman was referred for investigation of urticaria in March 1974. Since August 1972, the patient worked as a carver and model setter in a factory that made leather dresses. Since December 1973, she had had urticaria almost daily, most severely on the hands, and occasionally, edema of the lips. It was most intense in the afternoon. There was no sign of eczema, nor a history of skin diseases or atopy in the patient or her family. During the weekends and vacations when the patient had no contact with leather, there was no evidence of skin eruption.Physical examination showed no abnormalities. Findings
Helander I. Contact Urticaria From Leather Containing Formaldehyde. Arch Dermatol. 1977;113(10):1443. doi:10.1001/archderm.1977.01640100121026