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Article
October 1977

Antiacne Preparation

Author Affiliations

La Jolla, Calif

Arch Dermatol. 1977;113(10):1463. doi:10.1001/archderm.1977.01640100141046
Abstract

To the Editor.—  Recently, there has been considerable advertisement for an antiacne commerical preparation (Acne-Statin) in which the active ingredients are triclosan, methylparaben, and propylparaben. We report the results of tests using the material against Propionobacterium acnes, the probable pathogenic organism in acne vulgaris,1 and we include a photograph of colonies of facial organisms before and after application of this product (Figure).Using 6-mm filter paper disks that had been soaked in Acne-Statin formulation, and placing each disk on an agar plate that had been inoculated with a viable P acnes suspension, we found no inhibition of growth around four disks, and < 4-mm inhibition of growth around another four disks after anaerobic incubation at 37 C for five days.Infusion agar plate with 1% dextrose smeared with suspension of viable P acnes after five days anaerobic incubation at 37 C. (A) Disk soaked in Acne-Statin. (B) Disk soaked

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