• Four patients had thalassemia and leg ulcers. In three patients the hematologic diagnosis of thalassemia had not been previously made; the presenting symptom was the leg ulcer. The diagnosis of thalassemia should be considered in patients who have unexplained chronic leg ulcers; the incidence of this complication of thalassemia may be higher than previously reported.
(Arch Dermatol 113:1558-1560, 1977)
Stevens DM, Shupack JL, Javid J, Silber R. Ulcers of the Leg in Thalassemia. Arch Dermatol. 1977;113(11):1558-1560. doi:10.1001/archderm.1977.01640110078012