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January 1978

A Mechanobullous Disease of the NewbornBart's Syndrome

Author Affiliations

From the Department of Dermatology, University of California School of Medicine, San Francisco. Dr Smith is now in private practice in Louisville.

Arch Dermatol. 1978;114(1):81-84. doi:10.1001/archderm.1978.01640130045013

• A patient had a unique mechanobullous disease (Bart's syndrome). The characteristic congenital localized skin defects, trauma-induced erosions, and nail deformities are present. The inheritance pattern appears to be autosomal dominant but, as in this report, isolated cases have been recognized.

In a review of the other mechanobullous diseases, Bart's syndrome appears to present a distinctive clinical picture and course and has a favorable prognosis. The progressive spontaneous improvement emphasizes the importance of early recognition and conservative treatment.

(Arch Dermatol 114:81-84, 1978)