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Article
January 1978

Chronic Benign Familial PemphigusMinimal Involvement Mimicking Chronic Perianal Candidiasis

Author Affiliations

From the Department of Dermatology, University of Tennessee Health Sciences Center, Memphis.

Arch Dermatol. 1978;114(1):136. doi:10.1001/archderm.1978.01640130090042
Abstract

Most of the previous reports present chronic benign familial pemphigus (CBFP) in its full clinical expression, or nearly so (a notable exception was reported by Lyles et al).1

Report of a Case  A 26-year-old man with a six-year history of "raw skin" in a perianal distribution had been followed up from August 1973 until July 1976 by several physicians, including 17 visits to the Gailor Dermatology Clinic, Memphis. Candida sp had been cultured from macerated perianal skin on multiple occasions, and the patient received multiple courses of nystatincontaining topical ointments for moniliasis. The patient was examined for diabetes on several occasions and was always found to have a normal glucose tolerance. The patient reported that the dermatosis was worse during the summer with much pruritus and weeping and that in the winter, although there was never a complete healing, the symptoms were much less.On examination in July 1976,

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