[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
February 1978

Erythrokeratodermia VariabilisA Family Study

Author Affiliations

From the Department of Dermatology, State University of New York at Buffalo. Dr Gewirtzman is now in private practice in Plantation, Fla.

Arch Dermatol. 1978;114(2):259-261. doi:10.1001/archderm.1978.01640140077020

• Erythrokeratodermia variabilis is a rare genodermatosis; American authors have reported only four previous cases. It had been a problem to obtain a large pedigree for clinical investigation. We studied a family with 12 involved members in five generations.

Symmetrically distributed migratory patches and scaling plaques are characteristic and were found to involute with a combination of keratolytic agents and topical steroids. Exacerbations of these patches and plaques were noted in our female patients during such high estrogen states as pregnancy or oral contraceptive usage.

(Arch Dermatol 114:259-261, 1978)