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To the Editor.—
We read with great interest the results of O'Loughlin et al concerning IgE in atopic dermatitis and dermatosis (Archives 113:309-315, 1977). For four years we have performed more than 900 radioimmunosorbent tests in various dermatoses. We consider a value of IgE above 400 IU/ml to be pathological.Of 70 cases of atopic dermatitis, we found increased IgE levels in 71% of the patients. Spearman and Kendall's test shows an important relationship involving sex (higher level in man), age of onset of the disease, and anatomic extent, but no relationship wa found involving age, other allergic diseases, or blood eosinophilia.Increased IgE levels are seen in bullous pemphigoid, mycosis fungoides, and systemic lupus erythematosus. There is no notable change in localized neurodermatitis, contact dermatitis, nonspecific dermatitis, chronic urticaria, psoriasis, dysidrosis, ulcus cruris, scabies, systemic sclerosis, malignant lymphoma other than MF, bullous diseases other than bullous pemphigoid, and tinea
Amblard P, Reymond JL. IgE Levels in Various Dermatoses. Arch Dermatol. 1978;114(2):289-290. doi:10.1001/archderm.1978.01640140097037