March 1978

Reticular Pigmented Anomaly of the Flexures

Author Affiliations

From the Division of Dermatology, Departments of Internal Medicine (Dr Howell) and Pathology (Dr Freeman), University of Texas Health Science Center, Dallas.

Arch Dermatol. 1978;114(3):400-403. doi:10.1001/archderm.1978.01640150036011

• Reticular pigmented anomaly of the flexures (Dowling-Degos' anomaly) is a rare, benign, new genodermatosis that has recently evolved from independent observations and studies by several dermatologists. Because of its favorable prognosis, differentiation of this benign disorder from acanthosis nigricans, a cutaneous marker of possible or existing internal malignant disease, is highly important. Careful clinical appraisal of the eruption in correlation with the characteristic microscopic features makes the diagnosis simple and straightforward.

(Arch Dermatol 114:400-403, 1978)