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March 1978

Herpes Gestationis

Author Affiliations

Los Angeles

Arch Dermatol. 1978;114(3):448. doi:10.1001/archderm.1978.01640150084029

To the Editor.—  Since the report by Provost and Tomasi1 in 1973 of complement deposition along the basement membrane in skin of patients with herpes gestationis (HG), there have been a number of reports of immunofluorescence studies in this disease. We recently studied two patients with HG, in which results of immunofluorescence studies were helpful in confirming the diagnosis. Report of Cases.—Case 1.—A 30-year-old woman developed a highly pruritic generalized eruption at 18 weeks' gestation during her third pregnancy. Her first pregnancy had been normal. During her second pregnancy in 1974, she experienced a similar problem that persisted from the fifth month of gestation to the third postpartum day. On examination, her condition demonstrated grouped vesicles on an erythematous base and large, gyrate erythematous plaques with peripheral bullae, which measured up to 2 cm in diameter in a generalized distribution that spared only the scalp, face, palms, soles, and mucous

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