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April 1978

Epidermal Nucleolar IgG Deposition in Clinically Normal SkinClinical and Serologic Features of Eight Patients

Author Affiliations

From the Department of Dermatology, University of California Medical School, San Francisco (Drs Prystowsky and Tuffanelli); and the Department of Internal Medicine, University of Texas Southwestern Medical School, Dallas (Dr Gilliam).

Arch Dermatol. 1978;114(4):536-538. doi:10.1001/archderm.1978.01640160014004

• Epidermal nucleolar IgG deposition in clinically normal skin reflects high serum concentrations of antibody to nucleolar antigen. This immunopathologic finding occurred in six patients with scleroderma and in two patients with a scleroderma-systemic lupus erythermatosus overlap syndrome.

(Arch Dermatol 114:536-538, 1978)