• Epidermal nucleolar IgG deposition in clinically normal skin reflects high serum concentrations of antibody to nucleolar antigen. This immunopathologic finding occurred in six patients with scleroderma and in two patients with a scleroderma-systemic lupus erythermatosus overlap syndrome.
(Arch Dermatol 114:536-538, 1978)
Prystowsky SD, Gilliam JN, Tuffanelli DL. Epidermal Nucleolar IgG Deposition in Clinically Normal SkinClinical and Serologic Features of Eight Patients. Arch Dermatol. 1978;114(4):536-538. doi:10.1001/archderm.1978.01640160014004