• An umbilical nodule may be an early or late sign of metastasis from an internal location. To our knowledge, we are reporting the first case of carcinoid occurring as an umbilical mass.
The occurrence in our patient of idiopathic hyperparathyroidism, diabetes mellitus, and carcinoid suggests the diagnosis of multiple endocrine adenomatosis, type I, which may result from a developmental defect in the amine and amine precursor uptake and decarboxylation cell system.
(Arch Dermatol 114:570-572, 1978)
Brody HJ, Stallings WP, Fine RM, Someren A. Carcinoid in an Umbilical Nodule. Arch Dermatol. 1978;114(4):570-572. doi:10.1001/archderm.1978.01640160048014