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Article
April 1978

Dermatofibrosarcoma Protuberans With Lymph Node and Pulmonary Metastases

Author Affiliations

From the Departments of Pathology and Dermatology, University of Cape Town Medical School and Groote Schuur Hospital, Cape Town, South Africa.; Dr. Kahn is now with the Department of Pathology, University of North Carolina School of Medicine, Chapel Hill.

Arch Dermatol. 1978;114(4):599-601. doi:10.1001/archderm.1978.01640160077024
Abstract

• Dermatofibrosarcoma protuberans is a locally aggressive histiocytic tumor that, on rare occasions, may metastasize to regional lymph nodes or even to distant sites. We report a dermatofibrosarcoma protuberans with lymph node involvement in a 27-year-old woman. The tumor recurred repeatedly after local excisions, and ten years after the first resection, widespread pulmonary metastases developed in the patient and she died four years later. More than 400 patients with dermatofibrosarcoma protuberans have been reported in the literature; including the present case, five of these patients had lymph node metastases, 17 patients had hematogenous spread, and three had both lymphatic and blood-borne metastases.

(Arch Dermatol 114:599-601, 1978)

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