• Twelve of 54 patients with systemic lupus erythematosus (SLE) had nonpurpuric, chronic urticaria-like lesions. Skin biopsy of the lesions was performed in 11 cases, and nine showed necrotizing vasculitis. The 54 patients, in general, had severe disease, and laboratory and clinical data suggested a positive relationship between the urticaria-like lesions and disease severity. There was no consistent relationship between the course of the urticaria-like lesions and the serologic findings and clinical activity of the SLE. The frequency and importance of urticaria-like lesions in SLE deserve further study.
(Arch Dermatol 114:879-883, 1978)
O'Loughlin S, Schroeter AL, Jordon RE. Chronic Urticaria-Like Lesions in Systemic Lupus ErythematosusA Review of 12 Cases. Arch Dermatol. 1978;114(6):879-883. doi:10.1001/archderm.1978.01640180013003