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June 1978

Woronoff's Ring in Goeckerman Treatment of Psoriasis

Author Affiliations

Rochester, Minn

Arch Dermatol. 1978;114(6):963. doi:10.1001/archderm.1978.01640180093031

To the Editor.—  Recently, Woronoff's ring of psoriasis has been shown to be an area in which prostaglandins (PG) are absent or are synthesized in very low concentrations, perhaps as the result of an inhibitor of PG synthesis.1 It is also well established that ultraviolet (UV)-B damage to skin is mediated by PG activity as PG inhibitors, such as indomethacin and acetyl salicylic acid, inhibit the UV-B-induced erythema.2,3 We have observed the absence of sunburn in Woronoff's ring in psoriatic patients undergoing the modified Goeckerman treatment for psoriasis. Figure 1 demonstrates this phenomenon in a 50-year-old man with psoriasis who received a sunburn reaction during the Goeckerman treatment program. The psoriatic plaque involuted rapidly, as did Woronoff's ring, but the sunburn reaction resolved more slowly. Figure 2 demonstrates Woronoff's ring surrounding a psoriatic plaque in a 28-year-old woman. This is, in turn,Fig 1.—Sunburn reaction in 50-year-old psoriatic

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