• An infant had swirling hyperpigmentation, streaks of hypopigmentation, abnormal T-cell function, cleft palate, patent ductus arteriosus, and arrhinencephaly. This pattern of abnormalities is distinct from other disorders with abnormal pigmentation and malformations; such as incontinentia pigmenti, incontinentia pigmenti achromians, and the epidermal nevus syndrome.
(Arch Dermatol 114:1043-1044, 1978)
Ment L, Alper J, Sirota RL, Holmes LB. Infant With Abnormal Pigmentation, Malformations, and Immune Deficiency. Arch Dermatol. 1978;114(7):1043-1044. doi:10.1001/archderm.1978.01640190031010