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August 1978

Familial Primary Cutaneous AmyloidosisClinical, Genetic, and Immunofluorescent Studies

Author Affiliations

From the Department of Dermatology, Geisinger Medical Center, Danville, Penn.

Arch Dermatol. 1978;114(8):1173-1176. doi:10.1001/archderm.1978.01640200027007

• Familial primary cutaneous amyloidosis, a rare, autosomal dominant genodermatosis, affected 16 of 46 family members of German descent. Previous case reports involved families of Russian, Spanish, or Chinese descent. The finding of IgG, IgM, C3 in the amyloid deposits confirms recent reports of immunofluorescent dermal amyloid deposits.

(Arch Dermatol 114:1173-1176, 1978)