[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.159.129.152. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
October 1978

Diffuse Fasciitis With Eosinophilia

Author Affiliations

From the Department of Dermatology, University of Michigan Medical Center, Ann Arbor. Dr Callen is now with the Department of Dermatology, University of Louisville. Dr Chanda is now in private practice in Melbourne, Fla.

Arch Dermatol. 1978;114(10):1522-1524. doi:10.1001/archderm.1978.01640220071019
Abstract

• The recently described syndrome of diffuse fasciitis with eosinophilia consists of scleroderma-like cutaneous changes in the absence of Raynaud's phenomenon and without visceral involvement. Peripheral blood eosinophilia and hypergammaglobulinemia occur in the majority of patients. The biopsy specimen is characteristic and shows a diffusely thickened fascia with a noticeable inflammatory infiltrate. The etiology and pathogenesis of the entity are unknown. The majority of the cases have been reported to respond to corticosteroids. Pulmonary function abnormalities and rheumatoid factor elevation in one of our patients suggests that this syndrome may be a variant of scleroderma or may have previously unrecognized systemic manifestations. The patients' objective responses to corticosteroids were minimal.

(Arch Dermatol 114:1522-1524, 1978)

×