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—We too have felt that "stool burns" might be an important aspect of common chaffing, irritant forms of diaper rash. While these experiments were necessarily limited to a few hearty volunteers, we were unable to initiate a dermatitis in five volunteers despite repeated application of occlusive patch tests with fecal solutions (1% to 30%). Our limited experience in this area leads us to view fecal irritation as a possible secondary aggravating factor, but not capable of initiation of a diaper dermatitis.
Leyden JJ. Diaper Dermatitis-Reply. Arch Dermatol. 1978;114(10):1552. doi:10.1001/archderm.1978.01640220093033