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Article
October 1978

Genetic Syndrome

Author Affiliations

San Francisco

Arch Dermatol. 1978;114(10):1554. doi:10.1001/archderm.1978.01640220095039
Abstract

To the Editor.—  In the December 1977 issue of the Archives (113:1701-1704), Baden and Alper reported on a possible genetic syndrome that associated ichthyosiform dermatosis, keratitis, and deafness, but ignored the obvious probability that they are a manifestation of late congenital syphilis.Ichthyosis in congenital syphilis is well known and photographs in Allen's text resemble those of Baden and Alper.1 Neurosensory deafness and keratitis are two characteristic components of the Hutchinson's triad.2 Teeth, which are typically abnormal and form the third component (Hutchinson's incisors or mulberry molars), are not described, nor are serologic studies reported. The evidence, then, seems insufficient to establish a new constellation of signs, let alone one with a genetic basis.

Report of a Case.—  Deafness and keratitis developed some time after birth in a 35-year-old woman who was a juvenile diabetic. She had mild mental retardation, and her diabetes had been difficult to control.

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