• Precipitation of generalized pustular psoriasis was manifested in a patient with previously stable psoriasis vulgaris following lithium carbonate therapy for manic-depressive psychosis. Methotrexate toxicity was observed during the acute stage of the illness, and photochemotherapy was the successful treatment. Further pustulation occurred when lithium carbonate therapy was reintroduced.
(Arch Dermatol 114:1788-1789, 1978)
Lowe NJ, Ridgway HB. Generalized Pustular Psoriasis Precipitated by Lithium Carbonate. Arch Dermatol. 1978;114(12):1788-1789. doi:10.1001/archderm.1978.01640240030009