• Adult allergic contact dermatitis to the black ink of a felt-tip marker pen occurred in two adult subjects. In both subjects the cutaneous reaction did not require photoactivation.
Patch testing with the ingredients in the black ink demonstrated cutaneous sensitivity to the black dye. Further patch testing with the components of the black dye revealed cutaneous sensitivity in both subjects to the blue component, 1,4-bis(isopropylamino)anthraquinone, commonly known as Colour Index Solvent Blue 36.
(Arch Dermatol 114:1793-1794, 1978)
Miller MM, Goldberg HS, Wilkerson WG. Allergic Contact Dermatitis to 1,4-Bis(isopropylamino)anthraquinoneCaused by a Felt-Tip Marker Pen. Arch Dermatol. 1978;114(12):1793-1794. doi:10.1001/archderm.1978.01640240035011